Description

2-(Bromomethyl)Pyrimidine is a versatile brominated heterocyclic building block essential for advanced organic synthesis. Its reactive bromomethyl group makes it a critical intermediate for constructing complex molecules through nucleophilic substitution and cross-coupling reactions. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a building block for creating pyrimidine-based ligands for metal catalysis and organocatalysts.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology: Useful for introducing pyrimidine motifs into biomolecules or for creating molecular probes and tags.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and academic laboratories exploring new chemical entities.

Basic Information

Product Name	2-(Bromomethyl)Pyrimidine
CAS No.	54198-85-5
Molecular Formula	C5H5BrN2
Molecular Weight	173.01 g/mol
Synonyms	2-(Bromomethyl)pyrimidine; Pyrimidine, 2-(bromomethyl)-; 2-Pyrimidinylmethyl bromide; (Pyrimidin-2-yl)methyl bromide; Bromomethylpyrimidine; 2-Bromomethylpyrimidine; α-Bromo-2-picoline (pyrimidine analog); Contact for additional synonyms
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.