Description

Quinazoline, 1-Oxide (7Ci,9Ci) CAS NO 54145-20-9 is a specialized nitrogen-containing heterocyclic compound, specifically a quinazoline N-oxide derivative. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis for the development of novel active molecules. It is primarily required by research institutions and fine chemical manufacturers engaged in medicinal chemistry, agrochemical discovery, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or possessing anti-cancer properties.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, or plant growth regulators that utilize the quinazoline pharmacophore.
• Organic Synthesis Reagent: Employed in various organic transformations, including cyclization reactions and as a substrate for further functionalization of the N-oxide moiety.
• Material Science Research: Investigated for the development of organic electronic materials, ligands for metal complexes, or specialty polymers.

Basic Information

Product Name	Quinazoline, 1-Oxide (7Ci,9Ci)
CAS No.	54145-20-9
Molecular Formula	C8H6N2O
Molecular Weight	146.15 g/mol
Synonyms	1-Oxoquinazoline; Quinazoline N-Oxide; Quinazoline 1-Oxide; Quinazoline-1-oxide; 1H-Quinazoline 1-oxide; Quinazoline oxide; 1,3-Diazanaphthalene 1-oxide
EINECS	Contact for details

Quality Control

Our Quinazoline, 1-Oxide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a synthetic intermediate. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, supporting your R&D and scale-up activities. Specifications can be aligned with research-grade or GMP-starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.