Description

9-Chloro-5,6-Dihydro-4-Methyl-1-Phenyl-4H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine is a high-purity, heterocyclic organic compound of significant interest in advanced chemical synthesis. This compound matters as a key pharmaceutical intermediate and a versatile research chemical for developing novel active molecules. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the development of new therapeutic agents, particularly within the benzodiazepine analog space. The product, identified by CAS NO 54028-81-8, is supplied with stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold in drug discovery programs targeting central nervous system (CNS) disorders.
• Biochemical Research: Acts as a reference standard or ligand in pharmacological studies and receptor binding assays.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic Research: Utilized in universities and institutes for studying heterocyclic chemistry and reaction mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	9-Chloro-5,6-Dihydro-4-Methyl-1-Phenyl-4H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine
CAS No.	54028-81-8
Molecular Formula	C18H15ClN4
Molecular Weight	322.79 g/mol
Synonyms	9-Chloro-4-methyl-1-phenyl-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; 9-Chloro-5,6-dihydro-4-methyl-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; 54028-81-8; 9-Chloro-4-methyl-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; Lopirazepam Impurity; Triazolobenzodiazepine Derivative
EINECS	Contact for details

Quality Control

Our 9-Chloro-5,6-Dihydro-4-Methyl-1-Phenyl-4H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.