Description

3-(Pentafluoroethyl)Phenol is a high-purity fluorinated phenolic compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a pentafluoroethyl group, imparts exceptional chemical stability and specific electronic properties, making it invaluable for creating sophisticated materials and active pharmaceutical ingredients. This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for the development of next-generation products.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorinated phenol moiety can improve efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated monomers and additives in liquid crystal displays (LCDs) and other electronic materials, contributing to improved dielectric properties and thermal stability.
• Polymer Modification: Incorporated as a functional monomer or chain terminator to introduce fluorine into polymer backbones, enhancing chemical resistance, surface properties, and thermal performance of specialty plastics and coatings.
• Organic Synthesis Building Block: A versatile reagent for constructing complex aromatic and heterocyclic compounds in medicinal chemistry and material science research.

Basic Information

Product Name	3-(Pentafluoroethyl)Phenol
CAS No.	53998-04-2
Molecular Formula	C8H5F5O
Molecular Weight	212.12 g/mol
Synonyms	3-(Pentafluoroethyl)phenol; 3-(1,1,2,2,2-Pentafluoroethyl)phenol; Phenol, 3-(pentafluoroethyl)-; m-(Pentafluoroethyl)phenol; 3-Hydroxypentafluoroethylbenzene; 1-(3-Hydroxyphenyl)-2,2,2-trifluoro-1-(trifluoromethyl)ethanol (tautomer); Pentafluoroethylphenol
EINECS	Contact for details

Quality Control

Our 3-(Pentafluoroethyl)Phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant regulatory frameworks, including REACH and TSCA, for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.