Description

3-(1,1,2,2-Tetrafluoroethoxy)Phenol is a specialized fluorinated phenolic compound, serving as a high-value intermediate in advanced chemical synthesis. Its unique structure, featuring a tetrafluoroethoxy substituent, provides distinct electronic and steric properties critical for modifying material characteristics and biological activity. This compound is essential for R&D and production within the pharmaceutical, agrochemical, and advanced materials sectors, where precise fluorination is required to enhance product performance and stability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorinated group can enhance lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Advanced Material Research: A valuable reagent in R&D for creating specialty chemicals with tailored properties for high-performance applications.

Basic Information

Product Name	3-(1,1,2,2-Tetrafluoroethoxy)Phenol
CAS No.	53997-99-2
Molecular Formula	C8H6F4O2
Molecular Weight	210.13 g/mol
Synonyms	3-(Tetrafluoroethoxy)phenol; Phenol, 3-(1,1,2,2-tetrafluoroethoxy)-; 1-Hydroxy-3-(1,1,2,2-tetrafluoroethoxy)benzene; m-(Tetrafluoroethoxy)phenol; 3-Hydroxyphenyl tetrafluoroethyl ether; 53997-99-2; Tetrafluoroethoxy phenol derivative
EINECS	Contact for details

Quality Control

Every batch of 3-(1,1,2,2-Tetrafluoroethoxy)Phenol is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards and provide comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.