Description

Big Gastrin CAS NO 53988-98-0 is a synthetic peptide hormone analog of the endogenous gastrin peptide, which plays a critical role in stimulating gastric acid secretion. This high-purity compound is essential for advanced biochemical and pharmacological research, providing a reliable tool for studying gastrointestinal physiology and receptor interactions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on metabolic and digestive system studies.

Application

• Pharmacological Research: Used as a reference standard and agonist in studies of gastrin/CCK-B receptor signaling pathways and gastric acid secretion mechanisms.
• Biochemical Assay Development: Serves as a critical component in the development and validation of immunoassays (ELISA, RIA) for gastrin detection.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential therapeutic agents targeting gastrin-related disorders.
• Academic & Clinical Studies: Facilitates fundamental research into the physiology of the gastrointestinal tract, hormone regulation, and related pathologies.
• Diagnostic Manufacturing: Used as a calibrator or control material in the production of in vitro diagnostic (IVD) kits for measuring gastrin levels.

Basic Information

Product Name	Big Gastrin
CAS No.	53988-98-0
Molecular Formula	C97H124N18O31S2
Molecular Weight	2094.2 g/mol
Synonyms	Gastrin I (Human); Human Gastrin I; G-34; Gastrin-34; Little Gastrin I; HG-34; pGlu-Gly-Pro-Trp-Leu-(Glu)5-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2; L-Glutamine, N2-[N-[N-[N-[N-[N-[N-[N-[N-[N-[N-[N-[N-[N-[1-(aminocarbonyl)-2-phenylethyl]amino]carbonyl]-3-(4-hydroxyphenyl)-1-oxopropyl]amino]carbonyl]-1-oxobutyl]amino]carbonyl]-1-[(1-oxobutyl)amino]ethyl]amino]carbonyl]-1-[(1-oxobutyl)amino]ethyl]amino]carbonyl]-1-[(1-oxobutyl)amino]ethyl]amino]carbonyl]-1-[(1-oxobutyl)amino]ethyl]amino]carbonyl]-L-tryptophyl-L-methionyl-L-α-aspartyl-, 1-(5-oxo-L-prolyl)glycyl-L-prolyl-L-tryptophyl-L-leucyl-L-α-glutamyl-
EINECS	Contact for details

Quality Control

Our Big Gastrin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the product desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.