Description

6-Fluoro-2-Aminophenol is a versatile fluorinated aromatic building block, essential for synthesizing complex organic molecules. Its value lies in the unique reactivity imparted by the ortho-arranged amino and hydroxyl groups adjacent to a fluorine substituent, enabling precise molecular construction. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating advanced intermediates, active ingredients, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Functional Material Precursor: Employed in the production of advanced polymers, dyes, and liquid crystals where fluorination modifies electronic properties and solubility.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new fluorination chemistry and structure-activity relationships (SAR).
• Fine Chemical Manufacturing: Integral to custom synthesis and contract manufacturing of high-value, specialty fluorinated compounds.

Basic Information

Item	Detail
Product Name	6-Fluoro-2-Aminophenol
CAS No.	53981-25-2
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	2-Amino-6-fluorophenol; 6-Fluoro-2-hydroxyaniline; 2-Hydroxy-3-fluoroaniline; 3-Fluoro-2-aminophenol; 6-Fluoro-2-aminophenol; 6-Fluoro-o-aminophenol; 2-Amino-6-fluorohydroxybenzene; 53981-25-2
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2-Aminophenol is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.