Description

2-Amino-5-Fluorophenol is a versatile fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a hydroxyl group on a fluorinated benzene ring, makes it a high-value intermediate for creating complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting central nervous system disorders, anti-cancer agents, and anti-inflammatory medications.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a core component for producing high-performance, light-fast azo dyes and complex organic pigments.
• Liquid Crystal & OLED Materials: A valuable starting material for synthesizing fluorinated compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing properties like adhesion, thermal stability, and chemical resistance.
• Chemical Research & Development: A crucial reagent in academic and industrial R&D for exploring new synthetic pathways and developing novel fluorinated compounds.

Basic Information

Product Name	2-Amino-5-Fluorophenol
CAS No.	53981-24-1
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	5-Fluoro-2-aminophenol; 2-Amino-5-fluorophenol; 5-Fluoro-2-hydroxyaniline; 2-Hydroxy-5-fluoroaniline; 1-Amino-4-fluoro-2-hydroxybenzene; 5-Fluoro-2-aminophenol; 2-Hydroxy-5-fluoro-phenylamine; 5-Fluoro-o-aminophenol
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluorophenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and spectroscopic identification (IR, NMR). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your specific requirements. Our quality commitment supports applications in GMP-aligned environments and research requiring high-purity standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and tendency to oxidize, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maximize shelf life and maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	105 - 110 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.