Description

2-Amino-3-Fluorophenol is a versatile fluorinated aromatic building block, primarily valued for its role as a key intermediate in advanced organic synthesis. Its molecular structure, featuring both an amino and a hydroxyl group adjacent to a fluorine atom, makes it a critical precursor for constructing complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.
• Material Science Research: Acts as a monomer or modifier in the development of advanced polymers and liquid crystals with specific optical or electronic properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination reactions and heterocyclic chemistry.

Basic Information

Product Name	2-Amino-3-Fluorophenol
CAS No.	53981-23-0
Molecular Formula	C6H6FNO
Molecular Weight	127.12 g/mol
Synonyms	3-Fluoro-2-aminophenol; 2-Amino-3-fluorophenol; 3-Fluoro-2-hydroxyaniline; 2-Hydroxy-3-fluoroaniline; 3-Fluoroanthranilic alcohol; o-Amino-m-fluorophenol; 1-Amino-2-fluoro-6-hydroxybenzene; Benzenol, 2-amino-3-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and acids. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.