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Sar-Arg-Val-Tyr-Ile-His-Pro-Ala Acetate Salt CAS NO 53935-10-7


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CAS No.:53935-10-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Sar-Arg-Val-Tyr-Ile-His-Pro-Ala Acetate Salt is a synthetic peptide derivative of significant interest in advanced biochemical research and development. This compound, with the CAS registry number 53935-10-7, serves as a critical intermediate and reference standard for studying protease activity, peptide stability, and structure-activity relationships. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic and cardiovascular research.

Application

  • Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel peptide-based therapeutics targeting metabolic and cardiovascular pathways.
  • Biochemical Assay Development: Used as a high-purity substrate or reference standard in enzymatic assays to study protease kinetics and inhibition.
  • Academic Research: Employed in university and institutional labs for fundamental studies on peptide conformation, stability, and biological activity.
  • Biotechnology: Serves as a building block for the development of diagnostic tools, biosensors, and affinity purification systems.
  • Process Development & Scale-up: Used as a reference material for analytical method development and quality control during the scale-up of peptide manufacturing processes.

Basic Information

Product Name Sar-Arg-Val-Tyr-Ile-His-Pro-Ala Acetate Salt
CAS No. 53935-10-7
Molecular Formula C46H72N16O11 • xC2H4O2
Molecular Weight 1049.2 g/mol (free base)
Synonyms Sarcosyl-Arginyl-Valyl-Tyrosyl-Isoleucyl-Histidyl-Prolyl-Alanine Acetate; Sar-Arg-Val-Tyr-Ile-His-Pro-Ala-OH Acetate; Angiotensinogen (1-8) fragment, Sar1-Ala8 analog; [Sar1, Ala8]-Angiotensin I; H-Sar-Arg-Val-Tyr-Ile-His-Pro-Ala-OH acetate salt; Peptide substrate for renin/angiotensin system studies
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Quality Control

Every batch of Sar-Arg-Val-Tyr-Ile-His-Pro-Ala Acetate Salt is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA), providing data on purity (by HPLC), identity (by MS and NMR), and other critical parameters, is supplied with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For short-term use, store desiccated at 2-8°C.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 1.0%
Water Content (KF) ≤ 8.0%
Acetate Content (HPLC/IC) 1.0 - 3.0 eq
Peptide Content (Amino Acid Analysis) ≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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