Description

4-Chloro-2-(Trifluoromethyl)Phenol is a versatile halogenated phenolic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides valuable reactivity and stability for creating high-performance materials and active ingredients. This intermediate is essential for manufacturers in the agrochemical and pharmaceutical sectors seeking to develop novel products with enhanced properties.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of advanced herbicides, fungicides, and plant growth regulators, where the trifluoromethyl group enhances biological activity and environmental stability.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated phenolic motifs for target binding or metabolic resistance.
• Material Science: Employed in the production of specialty polymers, liquid crystals, and advanced resins, where it imparts specific thermal and chemical resistance properties.
• Dye and Pigment Synthesis: Acts as an intermediate for creating complex organic dyes and pigments, contributing to color fastness and molecular stability.
• Research & Development: Serves as a valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	4-Chloro-2-(Trifluoromethyl)Phenol
CAS No.	53903-51-8
Molecular Formula	C7H4ClF3O
Molecular Weight	196.55 g/mol
Synonyms	2-Trifluoromethyl-4-chlorophenol; 4-Chloro-α,α,α-trifluoro-o-cresol; 4-Chloro-2-(trifluoromethyl)phenol; 2-Hydroxy-5-chlorobenzotrifluoride; Phenol, 4-chloro-2-(trifluoromethyl)-; 5-Chloro-2-hydroxybenzotrifluoride; 4-Chloro-α,α,α-trifluoro-2-cresol; 4-Chloro-2-trifluoromethylphenol
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(Trifluoromethyl)Phenol adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent composition. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We are committed to meeting the rigorous standards required for GMP and ISO-aligned manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.