Description

4-Methoxy-2-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound that serves as a key building block in advanced organic synthesis. Its unique structure, featuring both a methoxy group and a trifluoromethyl substituent on the phenol ring, makes it a valuable intermediate for creating molecules with enhanced properties. This compound is particularly sought after by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as by research institutions and fine chemical manufacturers. Its utility stems from its ability to introduce both lipophilic and electron-withdrawing characteristics into target molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty polymers, imparting specific thermal or chemical resistance properties.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for constructing complex fluorinated aromatic compounds.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where fluorine substitution alters color and fastness properties.

Basic Information

Product Name	4-Methoxy-2-(Trifluoromethyl)Phenol
CAS No.	53903-50-7
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	2-Trifluoromethyl-4-methoxyphenol; 4-Methoxy-α,α,α-trifluoro-o-cresol; 2-Hydroxy-5-methoxybenzotrifluoride; 5-Methoxy-2-(trifluoromethyl)phenol; 4-Methoxy-2-(trifluoromethyl)benzenol; Phenol, 4-methoxy-2-(trifluoromethyl)-; o-Cresol, 4-methoxy-α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our production of 4-Methoxy-2-(Trifluoromethyl)Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to rigorous analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support applications requiring traceability and compliance with cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its phenolic and light-sensitive nature, prolonged exposure to light or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.