Description

2-Amino-5-Methoxybenzotrifluoride is a versatile trifluoromethyl-substituted aniline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a methoxy group adjacent to a trifluoromethyl moiety, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring trifluoromethyl groups to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transport layers in display and lighting technologies.
• Dye & Pigment Manufacturing: Intermediate for producing specialized dyes and pigments with improved lightfastness and color properties.
• Polymer & Resin Modifiers: Incorporated into polymer chains to impart specific characteristics like chemical resistance or altered refractive index.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D for constructing complex aromatic and heterocyclic compounds.

Basic Information

Product Name	2-Amino-5-Methoxybenzotrifluoride
CAS No.	53903-49-4
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	5-Methoxy-2-(trifluoromethyl)aniline; 2-Amino-5-methoxy-α,α,α-trifluorotoluene; 2-Trifluoromethyl-5-methoxyaniline; 5-Methoxy-2-aminobenzotrifluoride; 2-(Trifluoromethyl)-5-methoxyaniline; 5-Methoxy-α,α,α-trifluoro-o-toluidine; Benzenamine, 5-methoxy-2-(trifluoromethyl)-; 2-Trifluoromethyl-5-methoxybenzenamine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Methoxybenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports compliance with cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.