Description

L-Pipecolic acid hydrochloride is a high-purity, non-proteinogenic amino acid derivative widely utilized in pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for the synthesis of complex bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways.
• Peptide Mimetics Research: Used to incorporate the pipecolic acid scaffold into peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies and metabolic pathway analysis.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands for asymmetric catalysis and metal complex formation.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals, flavors, and fragrances.

Basic Information

Product Name	L-Pipecolic acid hydrochloride
CAS No.	53902-85-9
Molecular Formula	C6H11NO2 • HCl
Molecular Weight	165.62 g/mol
Synonyms	(S)-Piperidine-2-carboxylic acid hydrochloride; L-Homoproline hydrochloride; (S)-2-Piperidinecarboxylic acid hydrochloride; (-)-Pipecolic acid hydrochloride; L-Pipecolinic acid hydrochloride; (S)-Pipecolic acid HCl; L-2-Piperidinecarboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our L-Pipecolic acid hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.