Description

Ticlopidine Hydrochloride CAS NO 53885-35-1 is a potent antiplatelet agent belonging to the thienopyridine class of pharmaceuticals. Its primary value lies in its ability to prevent blood clot formation by irreversibly inhibiting the P2Y12 subtype of the ADP receptor on platelets. This makes it a critical active pharmaceutical ingredient (API) for the formulation of medications used to prevent thrombotic events. It is essential for pharmaceutical manufacturers and research institutions focused on cardiovascular therapeutics and hematology.

Application

• Primary Pharmaceutical Ingredient: Core API for the production of oral antiplatelet medications used to reduce the risk of stroke and heart attack.
• Cardiovascular Disease Prevention: Formulation of drugs for patients undergoing procedures like stent placement or those with conditions like peripheral arterial disease.
• Clinical Research & Development: Used as a reference standard and active compound in pharmacological studies exploring platelet aggregation and thrombosis.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of established antiplatelet therapies.
• Biochemical Research: Tool compound for investigating ADP-mediated signaling pathways in platelets and other cell types.
• Veterinary Pharmaceutical Applications: Potential use in developing antithrombotic treatments for animals in veterinary medicine.

Basic Information

Product Name	Ticlopidine Hydrochloride
CAS No.	53885-35-1
Molecular Formula	C14H14ClNS•HCl
Molecular Weight	300.24 g/mol (Free base: 263.79)
Synonyms	5-[(2-Chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride; Ticlopidine HCl; Ticlodone hydrochloride; Ticlopidina clorhidrato; Ticlopidinium chloride; PCR 3789; Tiklid; Ticlodix
EINECS	Contact for details

Quality Control

Our Ticlopidine Hydrochloride is manufactured and tested under strict quality management systems. It is produced to meet high-purity standards suitable for pharmaceutical applications, with typical grades aligning with pharmacopeial requirements. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as assay, related substances, residual solvents, and microbiological quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Microbiological Enumeration	Complies with Ph. Eur./USP guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.