Description

6-o-[3-Deoxy-3-(Methylamino)-α-D-Xylopyranosyl]-4-o-(2,6-Diamino-2,3,4,6-Tetradeoxy-α-D-Glycero-Hexa-4-Enopyranosyl)-2-Deoxy-D-Streptamine is a complex aminoglycoside derivative, a class of compounds known for their potent biological activity. This high-purity chemical intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel antibiotics and therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the development of next-generation anti-infective drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel aminoglycoside antibiotics and semi-synthetic derivatives.
• Antibacterial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) and mechanisms of action against resistant bacterial strains.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Medicinal Chemistry: A crucial starting material for medicinal chemists exploring modifications to the aminoglycoside scaffold to improve efficacy and reduce toxicity.
• Bioconjugation Studies: Potential use in the development of targeted drug delivery systems or diagnostic probes due to its functionalizable amine groups.

Basic Information

Product Name	6-o-[3-Deoxy-3-(Methylamino)-α-D-Xylopyranosyl]-4-o-(2,6-Diamino-2,3,4,6-Tetradeoxy-α-D-Glycero-Hexa-4-Enopyranosyl)-2-Deoxy-D-Streptamine
CAS No.	53797-16-3
Molecular Formula	C19H36N4O9
Molecular Weight	464.51 g/mol
Synonyms	2-Deoxy-6-O-[3-deoxy-3-(methylamino)-α-D-xylopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl)-D-streptamine; 4''-Deoxy-6'-N-methylamikacin; 6'-N-Methyl-4''-deoxyamikacin; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-6'-N-methyl-4''-deoxykanamycin A; A derivative of Amikacin; Antibiotic BB-K 8 derivative; (2S)-4-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4,6-diamino-3-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-2-hydroxyoxan-2-yl]oxy-4-[(2R,3R,4R,5R,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide
EINECS	Contact for details

Quality Control

Our 6-o-[3-Deoxy-3-(Methylamino)-α-D-Xylopyranosyl]-4-o-(2,6-Diamino-2,3,4,6-Tetradeoxy-α-D-Glycero-Hexa-4-Enopyranosyl)-2-Deoxy-D-Streptamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.