Description

6-o-[3-Deoxy-3-(Methylamino)-β-L-Arabinopyranosyl]-4-o-(2,6-Diamino-2,3,4,6-Tetradeoxy-α-D-Glycero-Hexa-4-Enopyranosyl)-2-Deoxy-D-Streptamine CAS NO 53759-50-5 is a complex aminoglycoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel antibacterial agents, particularly in the exploration of next-generation antibiotics targeting resistant bacterial strains. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of specialized therapeutic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthetic pathways for novel aminoglycoside antibiotics.
• Research & Development: Used as a high-purity reference standard in analytical method development and pharmacological studies.
• Biochemical Research: Employed in studies investigating bacterial ribosome interaction and mechanisms of antibiotic action.
• Active Pharmaceutical Ingredient (API) Synthesis: A crucial precursor in the cGMP-compliant manufacturing of specialized antibiotic compounds.
• Microbiology Studies: Utilized in research focused on overcoming bacterial resistance mechanisms.
• Standards and Metrology: Acts as a certified reference material (CRM) for quality control in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	6-o-[3-Deoxy-3-(Methylamino)-β-L-Arabinopyranosyl]-4-o-(2,6-Diamino-2,3,4,6-Tetradeoxy-α-D-Glycero-Hexa-4-Enopyranosyl)-2-Deoxy-D-Streptamine
CAS No.	53759-50-5
Molecular Formula	C20H38N6O9
Molecular Weight	506.55 g/mol
Synonyms	6'-N-Methylsisomicin; Antibiotic G 52; 6'-N-Methylgentamicin C1a; Sisomicin, 6'-N-methyl-; G-52 Antibiotic; 2-Deoxy-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl)-6-O-[3-deoxy-3-(methylamino)-β-L-arabinopyranosyl]streptamine; 6'-N-Methylsisomicin sulfate (salt form common)
EINECS	Contact for details

Quality Control

Our 6-o-[3-Deoxy-3-(Methylamino)-β-L-Arabinopyranosyl]-4-o-(2,6-Diamino-2,3,4,6-Tetradeoxy-α-D-Glycero-Hexa-4-Enopyranosyl)-2-Deoxy-D-Streptamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and related substances, to ensure it meets the high standards required for pharmaceutical research. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.