Description

Pyrimidine-1-Thiol CAS NO 53745-18-9 is a specialized heterocyclic organic compound featuring a pyrimidine ring substituted with a thiol group. This unique structure makes it a valuable building block and intermediate in advanced synthetic chemistry, particularly for creating sulfur-containing molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting enzymes or receptors where the thiol moiety is critical for activity.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Material Science Research: Employed in the development of advanced organic materials, such as conductive polymers or metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: The thiol group allows for use in bioconjugation techniques, linking molecules to proteins or other biomolecules.
• Chemical Biology Probes: Useful for synthesizing probes that study biological processes involving thiol reactivity or pyrimidine metabolism.

Basic Information

Product Name	Pyrimidine-1-Thiol
CAS No.	53745-18-9
Molecular Formula	C4H4N2S
Molecular Weight	112.15 g/mol
Synonyms	1H-Pyrimidine-1-thione; 1-Mercaptopyrimidine; Pyrimidine-1-thione; 1-Pyrimidinethiol; 1-Thiopyrimidine; NSC 403796; 1-Pyrimidinyl mercaptan
EINECS	Contact for details

Quality Control

Our Pyrimidine-1-Thiol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.