Description

(3Beta,5Beta,16Beta)-3-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-14,16-Dihydroxycard-20(22)-Enolide 16-Acetate is a high-purity cardiac glycoside derivative, a critical intermediate in pharmaceutical research and development. This compound is valued for its specific stereochemistry and functional groups, which are essential for studying structure-activity relationships in medicinal chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel cardiovascular therapeutics and for use as a reference standard in analytical testing.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthetic pathway for novel cardiac glycoside-based drugs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC/QA) of related pharmaceutical products.
• Biochemical Research: Employed in studies investigating the mechanism of action of cardiotonic steroids on sodium-potassium ATPase pumps.
• Medicinal Chemistry: A crucial substrate for structure-activity relationship (SAR) studies to optimize potency and reduce toxicity of cardiac agents.
• Academic Research: Utilized in university and institutional labs for pharmacological and toxicological studies.

Basic Information

Product Name	(3Beta,5Beta,16Beta)-3-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-14,16-Dihydroxycard-20(22)-Enolide 16-Acetate
CAS No.	53735-71-0
Molecular Formula	C31H44O10
Molecular Weight	576.68 g/mol
Synonyms	16-Acetylgitoxin; 16-Acetyl Gitoxin; 16-O-Acetylgitoxin; 3β-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl)oxy]-14β,16β-dihydroxy-5β-card-20(22)-enolide 16-acetate; Gitoxin 16-acetate; 16-Acetyl-3β-(digitoxosyloxy)-14β,16β-dihydroxy-5β-card-20(22)-enolide
EINECS	Contact for details

Quality Control

Our (3Beta,5Beta,16Beta)-3-[(2,6-Dideoxy-β-D-Ribo-Hexopyranosyl)Oxy]-14,16-Dihydroxycard-20(22)-Enolide 16-Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.