Description

(2E)-3-{[3-(Trifluoromethyl)Phenyl]Carbamoyl}Prop-2-Enoic Acid is a high-purity, synthetic organic compound featuring a trifluoromethylphenyl carbamoyl moiety attached to a prop-2-enoic acid backbone. This molecule is valued for its role as a versatile chemical intermediate and building block in advanced synthesis, particularly where the introduction of a trifluoromethyl group is required to modulate biological activity or material properties. It is primarily sought by pharmaceutical research and agrochemical development teams for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances bioavailability and efficacy.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystal materials requiring specific fluorinated components.
• Chemical Biology Probes: Employed in the development of molecular probes and inhibitors for studying enzyme function and signal transduction pathways.
• Organic Synthesis: Acts as a versatile Michael acceptor or a carboxylic acid derivative for constructing complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	(2E)-3-{[3-(Trifluoromethyl)Phenyl]Carbamoyl}Prop-2-Enoic Acid
CAS No.	53616-18-5
Molecular Formula	C11H8F3NO3
Molecular Weight	259.18 g/mol
Synonyms	(E)-3-((3-(Trifluoromethyl)phenyl)carbamoyl)acrylic acid; 3-[[3-(Trifluoromethyl)phenyl]carbamoyl]acrylic acid; 2-Propenoic acid, 3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]-, (2E)-; (2E)-3-({[3-(Trifluoromethyl)phenyl]amino}carbonyl)acrylic Acid; 3-(3-Trifluoromethyl-phenylcarbamoyl)-acrylic acid; α,β-Unsaturated carboxylic acid derivative; TFMPCA
EINECS	Contact for details

Quality Control

Our production of (2E)-3-{[3-(Trifluoromethyl)Phenyl]Carbamoyl}Prop-2-Enoic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.