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H-Beta,β-Dimethyl-D-Cys(Pmeobzl)-Oh CAS NO 53599-14-7
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CAS No.:53599-14-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
H-Beta,β-Dimethyl-D-Cys(Pmeobzl)-Oh is a specialized, non-proteinogenic amino acid derivative featuring a protected cysteine side chain. This compound is of significant value as a critical building block in the synthesis of complex peptides and peptidomimetics, where precise stereochemistry and side-chain protection are paramount. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced medicinal chemistry, drug discovery, and the development of novel therapeutic agents.
Application
- Peptide Synthesis: Serves as a key chiral intermediate for the solid-phase and solution-phase synthesis of custom peptides with specific structural motifs.
- Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, enzyme inhibitors, and receptor ligands.
- Medicinal Chemistry: Acts as a precursor for creating peptidomimetics designed to enhance metabolic stability and bioavailability of lead compounds.
- Bioconjugation: The protected thiol group can be strategically deprotected for site-specific labeling or conjugation with other molecules.
- Chemical Biology Probes: Employed in the construction of probes for studying protein-protein interactions and enzymatic activity.
- Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and amino acid chemistry.
Basic Information
| Item | Details |
|---|---|
| Product Name | H-Beta,β-Dimethyl-D-Cys(Pmeobzl)-Oh |
| CAS No. | 53599-14-7 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | D-3-(p-Methoxybenzylthio)-2,2-dimethyl-3-aminopropanoic Acid; Fmoc-D-Cys(Pmeobzl)-OH (pre-Fmoc deprotection); H-β,β-Dimethyl-D-Cys(Pmeobzl)-OH; (R)-2-Amino-3-[(4-methoxyphenyl)methylthio]-2-methylpropanoic Acid; Protected D-Cysteine derivative; β-dimethyl-D-cysteine(Pmeobzl) derivative; Boc-D-Cys(Pmeobzl)-OH (pre-Boc deprotection) |
| EINECS | Contact for details |
Quality Control
Our H-Beta,β-Dimethyl-D-Cys(Pmeobzl)-Oh is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity | ≥ 99.0% ee |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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