Description

H-Arg(Oh)-Oh Acoh is a chemically modified arginine derivative, specifically the acetate salt of Nω-hydroxy-L-arginine. This compound serves as a crucial intermediate and research chemical in advanced biochemical synthesis and pharmaceutical development. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutics and studying nitric oxide synthase pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nitric oxide synthase (NOS) inhibitors and other bioactive molecules.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to the L-arginine-nitric oxide pathway.
• Peptide Synthesis: Serves as a protected or modified arginine residue in the solid-phase and solution-phase synthesis of complex peptides.
• Cell Culture & Media Supplement: Potential component in specialized cell culture media for metabolic studies.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Preclinical Development: Utilized in the research and development stages of new drug candidates targeting cardiovascular and neurological systems.

Basic Information

Product Name	H-Arg(Oh)-Oh Acoh
CAS No.	53598-01-9
Molecular Formula	C8H19N5O5 • C2H4O2
Molecular Weight	321.30 g/mol (free base: 219.21 g/mol)
Synonyms	Nω-Hydroxy-L-arginine acetate salt; L-NG-Hydroxyarginine acetate; No-Hydroxy-L-arginine acetate; H-Arg(No-OH)-OH • HOAc; (2S)-2-Amino-5-[(amino-hydroxyamino)methylideneamino]pentanoic acid acetate; N5-[Amino(hydroxyamino)methylidene]-L-ornithine acetate; N-Hydroxyarginine acetate; Research Grade NOS Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our H-Arg(Oh)-Oh Acoh is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is assured through a comprehensive battery of analytical tests including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch. Production can adhere to cGMP guidelines for advanced research and pre-clinical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.