Description

L-Tyrosine Benzyl Ester p-Toluenesulfonate is a protected derivative of the essential amino acid L-Tyrosine, serving as a crucial building block in advanced organic synthesis. This compound is valued for its role in facilitating peptide coupling reactions while protecting the phenolic hydroxyl group, enabling the precise construction of complex biomolecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, diagnostic agents, and biochemical probes.

Application

• Peptide Synthesis: A key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS) for incorporating tyrosine residues.
• Pharmaceutical Research: Used in the R&D of novel peptide hormones, enzyme inhibitors, and targeted drug delivery systems.
• Bioconjugation: Serves as a precursor for creating fluorescent or affinity-labeled tyrosine analogs used in biochemical assays.
• Chemical Biology: Employed in the study of protein-protein interactions and post-translational modifications like phosphorylation.
• Academic Research: A standard reagent in university and institutional laboratories for teaching and method development in organic chemistry.
• API Intermediate: Potential use as a synthetic intermediate in the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	L-Tyrosine Benzyl Ester p-Toluenesulfonate
CAS No.	53587-11-4
Molecular Formula	C23H25NO6S
Molecular Weight	443.51 g/mol
Synonyms	L-Tyrosine, O-benzyl-, p-toluenesulfonate; H-Tyr(Bzl)-OH · TosOH; Benzyl L-tyrosinate p-toluenesulfonate; (S)-2-Amino-3-(4-(benzyloxy)phenyl)propanoic acid p-toluenesulfonate salt; L-Tyrosine benzyl ester tosylate salt; Tyrosine benzyl ester tosylate; NSC 334904; Fmoc-Tyr(Bzl)-OH precursor
EINECS	Contact for details

Quality Control

Our L-Tyrosine Benzyl Ester p-Toluenesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and residual solvent testing. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range available on COA
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.