Description

4-Amino-6-Iodopyrimidine is a halogenated pyrimidine derivative that serves as a versatile and critical building block in advanced organic synthesis. This compound matters for its unique molecular structure, which combines a reactive iodine atom with an amino group on the pyrimidine ring, enabling precise functionalization and cross-coupling reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Ligand and Catalyst Development: Utilized to synthesize complex nitrogen-containing ligands for coordination chemistry and catalysis.
• Diagnostic Reagent Precursor: Potential use in creating labeled compounds for biochemical assays and imaging.

Basic Information

Product Name	4-Amino-6-Iodopyrimidine
CAS No.	53557-69-0
Molecular Formula	C4H4IN3
Molecular Weight	221.00 g/mol
Synonyms	6-Iodo-4-pyrimidinamine; 4-Pyrimidinamine, 6-iodo-; 4-Amino-6-iodo-pyrimidine; 6-Iodo-4-aminopyrimidine; 4-Amino-6-iodo-1H-pyrimidine; 4-Amino-6-iodopyrimidine; 4-Amino-6-iodo-1H-pyrimidin-2-one (tautomer); AI3-52044
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Iodopyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.