Description

4-Trifluoroacetyl-p-Phenylenediamine is a high-purity, specialized aromatic amine derivative functionalized with a trifluoroacetyl group. This compound serves as a critical building block in advanced organic synthesis, offering unique reactivity and stability for creating complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as active pharmaceutical ingredient (API) synthesis and the development of specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic moieties for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group can improve biological activity and environmental persistence.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing high-performance polyamides, polyimides, and other specialty polymers with enhanced thermal and chemical resistance.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of complex, high-value dyes and pigments, especially for imaging and electronics applications.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies, ligand synthesis, and the creation of novel fluorinated compounds.
• Liquid Crystal & OLED Materials: A potential building block for fluorinated components in electronic display materials, contributing to improved performance characteristics.

Basic Information

Product Name	4-Trifluoroacetyl-p-Phenylenediamine
CAS No.	53446-90-5
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	1,4-Diamino-2-(trifluoroacetyl)benzene; p-Phenylenediamine, 4-(trifluoroacetyl)-; N1-[4-Aminophenyl]-2,2,2-trifluoroacetamide; 4-Amino-N-(4-aminophenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(4-aminophenyl)acetamide; 4-Trifluoroacetylaminoaniline; TFAPA; 4-TFAPA
EINECS	Contact for details

Quality Control

Our 4-Trifluoroacetyl-p-Phenylenediamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.