Description

4-[2-(1-Methyl-5-Nitro-1H-Imidazol-2-Yl)Ethenyl]-2-Pyrimidinamine is a specialized heterocyclic organic compound featuring a nitroimidazole core linked to an aminopyrimidine via an ethenyl bridge. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a critical building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential antiparasitic, antimicrobial, and anticancer agents.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Agrochemical Development: Building block for creating novel fungicides or herbicides with specific modes of action.
• Biochemical Probe Synthesis: Used to develop molecular probes for studying biological pathways and enzyme interactions.
• Organic Synthesis Reference Standard: High-purity material for analytical method development and validation.

Basic Information

Product Name	4-[2-(1-Methyl-5-Nitro-1H-Imidazol-2-Yl)Ethenyl]-2-Pyrimidinamine
CAS No.	53409-75-9
Molecular Formula	C₁₀H₁₀N₆O₂
Molecular Weight	246.23 g/mol
Synonyms	2-Pyrimidinamine, 4-[2-(1-methyl-5-nitro-1H-imidazol-2-yl)ethenyl]-; 4-[2-(1-Methyl-5-nitroimidazol-2-yl)vinyl]pyrimidin-2-amine; 4-[2-(1-Methyl-5-nitro-1H-imidazol-2-yl)vinyl]-2-pyrimidinamine; 4-(2-(1-Methyl-5-nitro-1H-imidazol-2-yl)vinyl)pyrimidin-2-amine; 53409-75-9; (E)-4-[2-(1-Methyl-5-nitroimidazol-2-yl)vinyl]pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our production of 4-[2-(1-Methyl-5-Nitro-1H-Imidazol-2-Yl)Ethenyl]-2-Pyrimidinamine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.