Description

Dansyl-L-Isoleucine Cyclohexylammonium Salt is a high-purity, dansyl-labeled derivative of the essential amino acid L-isoleucine. This compound is specifically designed for advanced analytical and research applications where precise detection and quantification are paramount. It serves as a critical reagent for scientists and quality control professionals in pharmaceutical development, proteomics, and biochemical research.

Application

• Amino Acid Analysis & Derivatization: Acts as a fluorescent derivatizing agent for the sensitive HPLC or LC-MS analysis of amino acids, enhancing detection limits.
• Peptide Synthesis & Sequencing: Used as a dansylated reference standard or building block in peptide chemistry for N-terminal labeling and tracking.
• Biomarker Research: Employed in metabolic studies and clinical research for the precise measurement of isoleucine and related metabolites.
• Pharmaceutical QC & Method Development: Serves as a certified reference material (CRM) for validating analytical methods in drug substance and finished product testing.
• Enzymology Studies: Utilized as a substrate or inhibitor in enzyme activity assays, particularly for proteases and amino acid metabolizing enzymes.
• Nutritional Science: Applied in research focused on protein digestion, amino acid absorption, and metabolic pathways.

Basic Information

Product Name	Dansyl-L-Isoleucine Cyclohexylammonium Salt
CAS No.	53369-40-7
Molecular Formula	C24H39N3O4S
Molecular Weight	465.65 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonyl-L-isoleucine cyclohexylammonium salt; Dansyl-L-Ile·CHA salt; Nε-Dansyl-L-isoleucine cyclohexylamine salt; L-Isoleucine, 5-(dimethylamino)-1-naphthalenesulfonyl-, compd. with cyclohexanamine (1:1); DNS-Ile·CHA; 1-Dimethylaminonaphthalene-5-sulfonyl-L-isoleucine cyclohexylammonium salt
EINECS	Contact for details

Quality Control

Our Dansyl-L-Isoleucine Cyclohexylammonium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 105.0% (on dried basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.