Description

(Dideacetoxy)Pancuronium CAS NO 53357-37-2 is a high-purity chemical intermediate, specifically a key derivative in the synthesis of neuromuscular blocking agents. Its precise chemical structure makes it a critical building block for pharmaceutical research and development, ensuring the integrity of complex drug synthesis pathways. This compound is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in advanced medicinal chemistry and the development of anesthetic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of Pancuronium bromide and related neuromuscular blocking agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new anesthetic and muscle relaxant compounds.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical labs.
• Process Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) within GMP environments.
• Biochemical Research: Utilized in studies investigating the mechanism of action at the neuromuscular junction.

Basic Information

Product Name	(Dideacetoxy)Pancuronium
CAS No.	53357-37-2
Molecular Formula	C35H60N2O4
Molecular Weight	572.87 g/mol
Synonyms	Pancuronium Impurity D; 2β,16β-Dipiperidino-5α-androstane-3α,17β-diol diacetate; 3α,17β-Diacetoxy-2β,16β-dipiperidino-5α-androstane; Desacetylpancuronium; Didesacetylpancuronium; Pancuronium Didesacetate; Norcuron Impurity D
EINECS	Contact for details

Quality Control

Our (Dideacetoxy)Pancuronium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.