Description

7-Fluoro-Dl-Tryptophan is a fluorinated derivative of the essential amino acid tryptophan, identified by CAS NO 53314-95-7. This modified amino acid is a critical building block in medicinal chemistry and biochemical research, where the introduction of a fluorine atom can significantly alter metabolic stability, bioavailability, and binding affinity. It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and academic researchers for developing novel bioactive compounds, enzyme inhibitors, and as a probe in metabolic studies.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of fluorinated drug candidates, particularly in oncology and neurology.
• Biochemical Research: Used as a non-natural amino acid probe to study enzyme mechanisms, protein structure-function relationships, and metabolic pathways.
• Agrochemical Development: Incorporated into the synthesis of advanced pesticides and herbicides where fluorine enhances stability and activity.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis to create fluorinated peptide analogs with modified properties.
• Metabolic Studies: Acts as a tracer or analog in research investigating tryptophan metabolism and related disorders.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	7-Fluoro-Dl-Tryptophan
CAS No.	53314-95-7
Molecular Formula	C₁₁H₁₁FN₂O₂
Molecular Weight	222.22 g/mol
Synonyms	7-Fluoro-DL-tryptophan; (±)-7-Fluorotryptophan; DL-7-Fluorotryptophan; 2-Amino-3-(7-fluoro-1H-indol-3-yl)propanoic acid; 7-Fluoro-DL-Trp; 7-F-Trp; 7-Fluoro-DL-α-amino-1H-indole-3-propanoic acid; 7-Fluoro-DL-β-3-indolylalanine
EINECS	Contact for details

Quality Control

Our 7-Fluoro-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.