Description

Ng-Monomethyl-L-Arginine Acetate is a high-purity, chemically modified derivative of the amino acid L-arginine, where a methyl group is attached to the guanidino nitrogen. This specific modification makes it a valuable biochemical tool and a critical intermediate in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for investigating nitric oxide synthase (NOS) pathways and synthesizing advanced peptide-based therapeutics.

Application

• Nitric Oxide Synthase (NOS) Research: Serves as a selective inhibitor in biochemical and pharmacological studies to investigate the role of nitric oxide in various physiological and pathological processes.
• Pharmaceutical Intermediate: Used as a key building block in the synthesis of novel peptide drugs and targeted therapeutic agents.
• Biochemical Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in laboratory settings.
• Enzyme Inhibition Studies: Employed in enzymatic assays to study arginine methylation and related metabolic pathways.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in cardiovascular biology, neurology, and immunology.

Basic Information

Product Name	Ng-Monomethyl-L-Arginine Acetate
CAS No.	53308-83-1
Molecular Formula	C9H19N5O2 • C2H4O2
Molecular Weight	291.31 g/mol (free base: 218.28 g/mol)
Synonyms	L-NMMA Acetate; NG-Monomethyl-L-arginine acetate salt; NG-Monomethyl-L-arginine acetate; MMA; Nω-Monomethyl-L-arginine acetate; (S)-2-Amino-5-[(methylamino)iminomethyl]aminopentanoic acid acetate; NG-Methyl-L-arginine acetate; Nitric Oxide Synthase Inhibitor I
EINECS	Contact for details

Quality Control

Our Ng-Monomethyl-L-Arginine Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of water vapor.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.