Description

1-[3-(Trifluoromethyl)Phenyl]Pyrido[2,3-D]Pyrimidin-4(1H)-One is a high-value, heterocyclic organic compound featuring a fused pyrido[2,3-d]pyrimidinone core substituted with a 3-(trifluoromethyl)phenyl group. This specialized chemical is a critical pharmaceutical intermediate and research building block for the development of novel active ingredients. It is primarily sought by pharmaceutical R&D organizations and fine chemical manufacturers engaged in drug discovery programs targeting kinase inhibition and other therapeutic pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of targeted kinase inhibitors and other small-molecule therapeutics.
• Drug Discovery Research: Serves as a core scaffold for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific biological pathways and enzyme functions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to create complex, high-value molecules for advanced applications.
• Agrochemical Research: Potential building block for developing new active ingredients in crop protection science.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]Pyrido[2,3-D]Pyrimidin-4(1H)-One
CAS No.	53277-57-9
Molecular Formula	C₁₅H₈F₃N₃O
Molecular Weight	303.24 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]pyrido[2,3-d]pyrimidin-4(1H)-one; 1-(3-(Trifluoromethyl)phenyl)pyrido[2,3-d]pyrimidin-4(1H)-one; 1-(3-Trifluoromethylphenyl)-1H-pyrido[2,3-d]pyrimidin-4-one; 1-(3-Trifluoromethylphenyl)pyrido[2,3-d]pyrimidin-4(1H)-one; 4(1H)-Pyrido[2,3-d]pyrimidinone, 1-[3-(trifluoromethyl)phenyl]-; CAS 53277-57-9
EINECS	Contact for details

Quality Control

Our production of 1-[3-(Trifluoromethyl)Phenyl]Pyrido[2,3-D]Pyrimidin-4(1H)-One adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.