Description

4,6(1H,5H)-Pyrimidinedione,Dihydro-5-(1H-Indol-3-Ylmethylene)-2-Thioxo- is a specialized heterocyclic organic compound that serves as a critical synthetic intermediate and building block in advanced chemical research. Its unique molecular architecture, featuring fused pyrimidine and indole-like moieties, makes it a valuable scaffold for developing novel active compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly those focused on medicinal chemistry and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new crop protection agents and pesticides.
• Biochemical Research: Employed in studies investigating enzyme inhibitors and receptor modulators due to its heterocyclic structure.
• Fine Chemical Synthesis: A versatile intermediate for creating complex molecules in custom synthesis and contract manufacturing.
• Academic Research: Used in universities and research institutes for fundamental studies in organic chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	4,6(1H,5H)-Pyrimidinedione,Dihydro-5-(1H-Indol-3-Ylmethylene)-2-Thioxo-
CAS No.	53215-61-5
Molecular Formula	C₁₃H₁₀N₄O₂S
Molecular Weight	286.31 g/mol
Synonyms	5-[(1H-Indol-3-yl)methylene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; Dihydro-5-(1H-indol-3-ylmethylene)-2-thioxo-4,6(1H,5H)-pyrimidinedione; 5-(Indol-3-ylmethylene)-2-thiobarbituric acid; 3H-Pyrimido[5,4-b]indole derivative; Thioxobarbituric acid indole derivative; 53215-61-5; 5-(1H-Indol-3-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione
EINECS	Contact for details

Quality Control

Our 4,6(1H,5H)-Pyrimidinedione,Dihydro-5-(1H-Indol-3-Ylmethylene)-2-Thioxo- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for identity confirmation and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.