Description

4-Hydroxy-2-Methylpyrimidine-5-Carboxamide is a high-purity pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for creating complex molecules with specific biological and chemical activities. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the pyrimidine core imparts specific biological activity.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other specialty chemicals requiring a functionalized pyrimidine structure.
• Biochemical Research: Employed as a standard or reagent in biochemical studies and enzymatic assays involving nucleotide analogs or metabolic pathways.
• Material Science: Potential use as a monomer or additive in the synthesis of polymers and advanced materials with tailored properties.

Basic Information

Product Name	4-Hydroxy-2-Methylpyrimidine-5-Carboxamide
CAS No.	53135-25-4
Molecular Formula	C6H7N3O2
Molecular Weight	153.14 g/mol
Synonyms	5-Carbamoyl-2-methylpyrimidin-4-ol; 2-Methyl-4-hydroxypyrimidine-5-carboxamide; 4-Hydroxy-2-methyl-5-pyrimidinecarboxamide; 5-Pyrimidinecarboxamide, 4-hydroxy-2-methyl-; 4-Hydroxy-2-methylpyrimidine-5-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Methylpyrimidine-5-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.