Description

4-Hydroxy-2-Methyl-Pyrimidine-5-Carboxylic Acid Ethyl Ester is a high-purity pyrimidine derivative, a crucial heterocyclic building block valued for its role in synthesizing complex organic molecules. Its significance lies in providing a versatile scaffold for pharmaceutical and agrochemical research and development, enabling the creation of novel compounds with targeted biological activity. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the pyrimidine core.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, dyes, and complex ligands for catalysis.
• Academic & Industrial R&D: Employed in medicinal chemistry and organic synthesis laboratories for method development and exploring new chemical entities.
• Material Science Research: Investigated as a potential monomer or additive for creating functional polymers and advanced materials.

Basic Information

Product Name	4-Hydroxy-2-Methyl-Pyrimidine-5-Carboxylic Acid Ethyl Ester
CAS No.	53135-24-3
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	Ethyl 4-Hydroxy-2-methylpyrimidine-5-carboxylate; 5-Ethoxycarbonyl-4-hydroxy-2-methylpyrimidine; 2-Methyl-4-oxo-3,4-dihydropyrimidine-5-carboxylic acid ethyl ester; 4-Hydroxy-2-methyl-5-pyrimidinecarboxylic acid ethyl ester; NSC 163044; Ethyl 4-hydroxy-2-methyl-5-pyrimidinecarboxylate; 5-Carbethoxy-4-hydroxy-2-methylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Methyl-Pyrimidine-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.