Description

2,3,4,5-Tetrafluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the tetrafluoro substitution pattern, which makes it a critical intermediate for creating high-performance materials and active pharmaceutical ingredients. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates where fluorine substitution enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorobenzyl moiety can improve lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated as a monomer or cross-linking agent to produce specialty polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis Building Block: A valuable reagent for nucleophilic substitution reactions, esterifications, and ether formations to create complex fluorinated aromatic structures.
• Material Science Research: Employed in academic and industrial R&D for developing new fluorinated compounds with tailored properties for advanced applications.

Basic Information

Product Name	2,3,4,5-Tetrafluorobenzyl Alcohol
CAS No.	53072-18-7
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	(2,3,4,5-Tetrafluorophenyl)methanol; 2,3,4,5-Tetrafluorobenzenemethanol; α,2,3,4-Tetrafluoro-benzenemethanol; Tetrafluorobenzyl Alcohol; Benzyl alcohol, 2,3,4,5-tetrafluoro-; 53072-18-7; Perfluorobenzyl Alcohol (common name variant)
EINECS	Contact for details

Quality Control

Our 2,3,4,5-Tetrafluorobenzyl Alcohol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent quality suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.