Description

5-Ethyl-5-Phenyl-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized silylated pyrimidinetrione derivative, serving as a key synthetic intermediate and protecting group reagent in advanced organic synthesis. Its value lies in providing a protected, reactive scaffold for constructing complex heterocyclic systems, particularly in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on novel active ingredients, where precise molecular manipulation is required.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel barbiturate analogs and other central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its heterocyclic core for bioactivity.
• Advanced Material Synthesis: Serves as a precursor for creating specialized polymers and ligands with unique thermal or chemical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, particularly in exploring new silylation and heterocycle formation reactions.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for high-value fine chemicals, where its trimethylsilyl groups offer strategic advantages in reactivity and purification.

Basic Information

Product Name	5-Ethyl-5-Phenyl-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	52937-73-2
Molecular Formula	C19H30N2O3Si2
Molecular Weight	390.63 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-ethyl-5-phenylbarbituric acid; 5-Ethyl-5-phenyl-1,3-bis(trimethylsilyl)barbituric acid; 5-Ethyl-1,3-bis(trimethylsilyl)-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione; NSC 339586; Silylated 5,5-Disubstituted Barbituric Acid Derivative; TMS-Barbiturate Derivative
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-Phenyl-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.