Description

5-(1-Methylpropyl)-5-(2-Propenyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon-protected pyrimidinetrione derivative, a key intermediate in advanced organic synthesis. Its value lies in providing a reactive, yet protected, heterocyclic core that enables precise chemical transformations under controlled conditions. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a protected precursor for the synthesis of novel barbiturate analogs and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in developing new active ingredients for crop protection, leveraging its heterocyclic structure.
• Organic Synthesis Building Block: The trimethylsilyl (TMS) groups act as protective moieties, allowing for selective functionalization at other reactive sites on the pyrimidinetrione ring.
• Material Science Precursor: Potential use in creating silicon-incorporated organic frameworks or polymers with specific thermal or electronic properties.
• Chemical Research & Development: A valuable tool for methodological studies in heterocyclic chemistry and protective group strategies.

Basic Information

Product Name	5-(1-Methylpropyl)-5-(2-Propenyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	52937-69-6
Molecular Formula	C17H32N2O3Si2
Molecular Weight	368.62 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-(1-methylpropyl)-5-(2-propenyl)-2,4,6-pyrimidinetrione; 5-sec-Butyl-5-allyl-1,3-bis(trimethylsilyl)barbituric acid; 5-Allyl-5-sec-butyl-1,3-bis(trimethylsilyl)barbituric acid; TMS-protected sec-butyl-allyl barbituric acid; sec-Butyl-allyl-bis(trimethylsilyl) barbiturate; 52937-69-6; Allyl-sec-butyl-bis-TMS barbiturate
EINECS	Contact for details

Quality Control

Our production of 5-(1-Methylpropyl)-5-(2-Propenyl)-1,3-Bis(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles. While produced as a fine chemical intermediate, our quality systems are designed to support cGMP and ISO standards for traceability and documentation, meeting the rigorous demands of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.