Description

Hemoglobin Ankara CAS NO 52933-31-0 is a specific, well-characterized variant of hemoglobin, a critical oxygen-transporting metalloprotein found in red blood cells. This compound is of significant value in biochemical and medical research for studying hemoglobinopathies, oxygen-binding kinetics, and protein stability. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in hematology research, the development of blood substitutes, and the study of sickle cell disease mechanisms.

Application

• Biomedical Research: As a model protein for investigating the structure-function relationships of hemoglobin variants, oxygen affinity, and allosteric regulation.
• Diagnostic Development: Used as a reference standard or key component in the calibration and development of diagnostic assays for hemoglobin disorders.
• Hematology Studies: Essential for in-vitro studies related to sickle cell disease, thalassemia, and other hemoglobinopathies to understand disease pathology and evaluate potential therapeutic interventions.
• Biochemical Reagent: Serves as a high-purity biochemical reagent in enzymatic studies, protein chemistry, and as a substrate in various experimental protocols.
• Pharmaceutical R&D: Employed in research focused on novel oxygen therapeutics, blood substitutes, and drug delivery systems that leverage hemoglobin's oxygen-carrying capacity.
• Educational & Reference Material: Used in academic and teaching laboratories for advanced biochemistry and molecular biology courses.

Basic Information

Product Name	Hemoglobin Ankara
CAS No.	52933-31-0
Molecular Formula	C2952H4664N812O832S40Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb Ankara; Hemoglobin variant Ankara; HBB:c.94G>C; Hemoglobin (human variant Ankara); β-87 Thr->Pro Hemoglobin; Unstable Hemoglobin Ankara; Hemoglobin A (variant); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Hemoglobin Ankara is produced and handled under stringent quality protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and biological activity. Certificates of Analysis (COA) are provided, detailing key parameters such as spectral purity, methemoglobin content, and endotoxin levels. We adhere to relevant guidelines for research-grade biochemicals to ensure batch-to-batch consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For in-use solutions, store at 2-8°C and use promptly.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (IR/Spectrophotometry)	Conforms to standard
Purity (HPLC)	≥ 95% (Hemoglobin Ankara)
Methemoglobin Content	< 5%
Protein Content (Biuret)	≥ 90%
Oxygen Binding Capacity	Assayed, COA provided
Endotoxin	< 1.0 EU/mg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.