Description

H-Pro-Val-Oh CAS NO 52899-09-9 is a high-purity, protected dipeptide building block, specifically L-Prolyl-L-valine. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure and sequence. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, development of bioactive peptides, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of therapeutic peptides targeting metabolic and neurological disorders.
• Peptidomimetic Research: Serves as a core scaffold in the design and development of novel peptidomimetics with enhanced stability and bioavailability.
• Bioconjugation: Used in the preparation of peptide-protein conjugates for diagnostic assays and targeted drug delivery systems.
• Biochemical Research: Essential reagent for studying enzyme-substrate interactions, protease specificity, and peptide folding mechanisms.
• Cosmetic Peptides: A potential precursor in the synthesis of bioactive peptides for advanced skincare formulations aimed at anti-aging and skin repair.

Basic Information

Product Name	H-Pro-Val-Oh
CAS No.	52899-09-9
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	L-Prolyl-L-valine; H-Pro-Val-OH; Pro-Val; (S)-2-((S)-Pyrrolidine-2-carboxamido)-3-methylbutanoic acid; L-Valine, L-prolyl-; Boc-Pro-Val-OH (protected form); Fmoc-Pro-Val-OH (protected form); Z-Pro-Val-OH (protected form)
EINECS	Contact for details

Quality Control

Our H-Pro-Val-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	-70° to -80° (c=1, in AcOH)
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.