Description

6-Bromo-2-(Trifluoromethyl)Pyrido[2,3-D]Pyrimidin-4(3H)-One is a high-value, multi-functional heterocyclic building block, distinguished by its bromo and trifluoromethyl substituents which impart unique reactivity and physicochemical properties. This compound is essential for advanced research and development, particularly in the synthesis of novel, complex molecules. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for applications in medicinal chemistry, crop protection, and organic electronics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging the pyridopyrimidine core for bioactivity.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science: Serves as a specialized building block for creating organic semiconductors and light-emitting materials for electronic devices.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromo substituent, enabling rapid diversification of molecular libraries.
• Bioconjugation & Probe Development: Acts as a handle for attaching fluorescent tags or other functional groups in biochemical probe design.

Basic Information

Product Name	6-Bromo-2-(Trifluoromethyl)Pyrido[2,3-D]Pyrimidin-4(3H)-One
CAS No.	52833-43-9
Molecular Formula	C8H3BrF3N3O
Molecular Weight	294.03 g/mol
Synonyms	6-Bromo-2-(trifluoromethyl)-3,4-dihydropyrido[2,3-d]pyrimidin-4-one; 6-Bromo-2-(trifluoromethyl)-4H-pyrido[2,3-d]pyrimidin-4-one; 6-Bromo-2-trifluoromethyl-3H-pyrido[2,3-d]pyrimidin-4-one; 6-Bromo-2-trifluoromethylpyrido[2,3-d]pyrimidin-4(3H)-one; 52833-43-9; 6-Bromo-2-(trifluoromethyl)-4(3H)-pyrido[2,3-d]pyrimidinone
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-2-(Trifluoromethyl)Pyrido[2,3-D]Pyrimidin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and cGMP-grade requirements, with quality systems designed to meet the standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.