Description

3-(Trifluoromethoxy)Benzaldehyde is a versatile fluorinated aromatic aldehyde building block, distinguished by the presence of a trifluoromethoxy substituent. This compound is highly valued for its ability to introduce both aldehyde and trifluoromethoxy functionalities into target molecules, enhancing their lipophilicity and metabolic stability. It is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active ingredients, and functional materials.

Application

• Pharmaceutical Intermediates: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifiers: Incorporated to create specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis: Employed in various name reactions (e.g., Grignard, Wittig, reductive amination) to construct complex molecular architectures in academic and industrial research.
• Dye & Pigment Manufacturing: Acts as a starting material for synthesizing specialized fluorinated dyes and pigments.

Basic Information

Product Name	3-(Trifluoromethoxy)Benzaldehyde
CAS No.	52771-21-8
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	m-(Trifluoromethoxy)benzaldehyde; 3-(Trifluoromethoxy)benzaldehyde; Benzaldehyde, 3-(trifluoromethoxy)-; α-Oxo-3-(trifluoromethoxy)toluene; 3-Trifluoromethoxybenzaldehyde; m-Trifluoromethoxybenzaldehyde; 3-Carboxybenzotrifluoromethoxy aldehyde (incorrect but sometimes used in searches)
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is compatible with strong acid/organic solvent. Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.