Description

4-Pyrimidinecarbonyl Chloride, 5-Chloro-1,2,3,6-Tetrahydro-2,6-Dioxo- (9Ci) is a high-purity, reactive heterocyclic building block essential for advanced organic synthesis. Its core value lies in its dual functionality as an acid chloride and a halogenated pyrimidine derivative, enabling efficient construction of complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic libraries in medicinal chemistry and material science.
• Peptide Mimetics & Conjugation: The reactive carbonyl chloride group facilitates amide bond formation for creating peptide-like structures or bioconjugates.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	4-Pyrimidinecarbonyl Chloride, 5-Chloro-1,2,3,6-Tetrahydro-2,6-Dioxo- (9Ci)
CAS No.	52759-28-1
Molecular Formula	C5H2Cl2N2O3
Molecular Weight	208.99 g/mol
Synonyms	5-Chloro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbonyl chloride; 5-Chloro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarbonyl chloride; 5-Chlorobarbituric acid-4-carbonyl chloride; 4-(Chlorocarbonyl)-5-chloropyrimidine-2,6(1H,3H)-dione; 5-Chloro-2,4,6-trioxohexahydropyrimidine-4-carbonyl chloride; 5-Chlorobarbituryl-4-carbonyl chloride; 5-Chloro-2,6-dihydroxypyrimidine-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinecarbonyl Chloride, 5-Chloro-1,2,3,6-Tetrahydro-2,6-Dioxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.