Description

Luteinizing Hormone-Releasing Factor (Swine), 5-L-Phenylalanine-, Acetate (Salt), Hydrate is a synthetic analog of the native gonadotropin-releasing hormone (GnRH), specifically modified with a D-amino acid substitution at position 6. This modification confers enhanced potency and metabolic stability, making it a critical tool for research and development in endocrinology. It is primarily utilized by pharmaceutical researchers, diagnostic manufacturers, and biotechnology companies for advanced studies in reproductive biology, hormone regulation, and therapeutic agent development. The compound is supplied as a high-purity, lyophilized powder to ensure reliable and consistent experimental results.

Application

• Pharmaceutical Research & Development: As a reference standard and active agent in the development of novel therapeutics targeting hormonal disorders, fertility treatments, and certain cancers.
• Diagnostic Manufacturing: Used in the production and calibration of immunoassay kits for the quantitative measurement of related hormones in clinical and research settings.
• Biochemical Studies: A key reagent for investigating the structure-activity relationships (SAR) of GnRH analogs and their interaction with receptor proteins.
• Veterinary Science: Applied in reproductive management and fertility studies for livestock and other animals.
• Academic Research: Serves as an essential tool in university and institutional labs for fundamental studies in neuroendocrinology and peptide hormone signaling pathways.

Basic Information

Product Name	Luteinizing Hormone-Releasing Factor (Swine), 5-L-Phenylalanine-, Acetate (Salt), Hydrate
CAS No.	52699-48-6
Molecular Formula	C64H88N18O14 • xC2H4O2 • yH2O
Molecular Weight	~1302.5 g/mol (anhydrous free base)
Synonyms	5-D-Phenylalanine Luteinizing Hormone-Releasing Factor (Swine); [D-Phe6]-GnRH (Swine); Gonadorelin (5-D-Phenylalanine) analog; LHRH (5-D-Phe); GnRH agonist (D-Phe6); Fertirelin Acetate (related analog); Luliberin (5-D-Phenylalanine) derivative; Pyro-Glu-His-Trp-Ser-Tyr-D-Phe-Leu-Arg-Pro-Gly-NH2 Acetate
EINECS	Contact for details

Quality Control

Our Luteinizing Hormone-Releasing Factor (Swine), 5-L-Phenylalanine-, Acetate (Salt), Hydrate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	2.0 - 8.0%
Peptide Content (UV)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.