Description

Lysine(Succinyl)-Oh is a modified amino acid derivative where the ε-amino group of lysine is succinylated. This specific chemical modification is crucial for creating advanced intermediates in peptide synthesis and bioconjugation chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the solid-phase synthesis of complex peptides and peptidomimetics for drug discovery.
• Bioconjugation Reagent: Used to introduce a carboxylic acid functional group via the succinyl moiety for coupling proteins, antibodies, or other biomolecules to carriers, labels, or solid supports.
• Linker Chemistry: Acts as a spacer or linker in the design of drug delivery systems, such as antibody-drug conjugates (ADCs), due to its defined chain length and functional handles.
• Biochemical Research: Employed in proteomics and enzymology studies to modify lysine residues, investigating protein structure, function, and interactions.
• Material Science: Utilized in the synthesis of functionalized polymers and hydrogels for biomedical applications, including tissue engineering scaffolds.

Basic Information

Product Name	Lysine(Succinyl)-Oh
CAS No.	52685-16-2
Molecular Formula	C10H18N2O5
Molecular Weight	246.26 g/mol
Synonyms	N6-Succinyl-L-lysine; Nε-Succinyl-L-lysine; Succinyllysine; L-Lysine, N6-succinyl-; N6-(3-Carboxypropionyl)-L-lysine; (2S)-2-Amino-6-[(3-carboxypropanoyl)amino]hexanoic acid; Nε-Succinyl-L-lysine-OH; Succ-Lys-OH
EINECS	Contact for details

Quality Control

Our Lysine(Succinyl)-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). Certificates of Analysis (COA) detailing all specifications are provided to ensure the material meets the stringent requirements for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.