Description

(Phenylmethoxy)Carbonylcysteinyl(Phenylmethyl)-Tyrosyl-Isoleucine tert-Butyl Ester is a protected peptide building block, a crucial intermediate in the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics. Its value lies in providing a precisely defined sequence fragment, enabling researchers and manufacturers to efficiently construct larger, biologically active peptide targets with high fidelity. This compound is essential for pharmaceutical R&D, biotechnology, and academic laboratories focused on developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of therapeutic peptides targeting metabolic disorders, oncology, and infectious diseases.
• Peptide Library Construction: Used in combinatorial chemistry for generating diverse peptide libraries for high-throughput screening and drug discovery.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides used in imaging, diagnostics, and target identification studies.
• Academic & Contract Research: Fundamental reagent for research into peptide structure-activity relationships (SAR) and novel synthetic methodologies.
• API Synthesis: Intermediate in the multi-step production of Active Pharmaceutical Ingredients (APIs) for peptide-based drugs.
• Biochemical Research: Used to study enzyme-substrate interactions, receptor binding, and other fundamental biological processes.

Basic Information

Product Name	(Phenylmethoxy)Carbonylcysteinyl(Phenylmethyl)-Tyrosyl-Isoleucine tert-Butyl Ester
CAS No.	52668-03-8
Molecular Formula	C41H52N4O8S
Molecular Weight	760.94 g/mol
Synonyms	Z-Cys(Bzl)-Tyr-Ile-OtBu; N-[(Benzyloxy)carbonyl]-S-benzyl-L-cysteinyl-L-tyrosyl-L-isoleucine 1,1-Dimethylethyl Ester; Boc-Cys(Bzl)-Tyr-Ile-OtBu (common naming convention); FMOC-Cys(Trt)-Tyr-Ile-OtBu (related protected form); Z-Cys(Bzl)-Tyr-Ile-t-Butyl Ester; CBZ-Cysteine(Benzyl)-Tyrosine-Isoleucine tert-Butyl Ester; N-Carbobenzoxy-S-benzylcysteinyltyrosylisoleucine tert-butyl ester; Protected Tripeptide Ester 52668-03-8
EINECS	Contact for details

Quality Control

Our peptide intermediates are produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and MS, NMR for structural confirmation, to ensure consistency and identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical research and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below for long-term stability. This compound is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation. Store in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion [M+H]+
Purity (HPLC)	≥ 95.0% (Area %)
Assay	≥ 97.0% (by NMR)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.