Description

Furan-3-Sulfonyl Chloride is a versatile and highly reactive organosulfur compound, serving as a crucial sulfonylation reagent in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the furan-3-sulfonyl moiety, a key functional group for modulating the physicochemical and biological properties of target molecules. This intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the furan-sulfonyl pharmacophore.
• Material Science Precursor: Employed in the creation of specialized polymers, ligands for catalysis, and advanced organic frameworks with tailored properties.
• Chemical Biology Probes: Utilized to synthesize activity-based probes and labeling reagents for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	Furan-3-Sulfonyl Chloride
CAS No.	52665-49-3
Molecular Formula	C₄H₃ClO₃S
Molecular Weight	166.58 g/mol
Synonyms	3-Furansulfonyl chloride; 3-Furoylsulfonyl chloride; Furan-3-sulfonic acid chloride; 3-Thiophenesulfonyl chloride (isomeric); β-Furansulfonyl chloride
EINECS	Contact for details

Quality Control

Our Furan-3-Sulfonyl Chloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.