Description

Dobutamine Hydrochloride CAS NO 52663-81-7 is a synthetic catecholamine and a potent, selective β-1 adrenergic receptor agonist. This compound is of critical importance in the pharmaceutical industry as a key active pharmaceutical ingredient (API) for cardiovascular therapeutics. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of injectable solutions used in cardiac stress testing and the treatment of acute heart failure.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations for the short-term treatment of patients with cardiac decompensation.
• Cardiac Stress Testing: Used in pharmacological stress echocardiograms to assess coronary artery disease and myocardial viability.
• Clinical Research: Serves as a reference standard and biochemical tool in cardiovascular and adrenergic receptor research studies.
• Hospital Compounding: Utilized in hospital pharmacy settings for preparing specific dosage solutions under aseptic conditions.
• Veterinary Medicine: Applied in critical care veterinary settings for supporting cardiac function in animals.

Basic Information

Product Name	Dobutamine Hydrochloride
CAS No.	52663-81-7
Molecular Formula	C18H23NO3 • HCl
Molecular Weight	337.84 g/mol
Synonyms	Dobutamine HCl; (±)-4-[2-[[1-Methyl-3-(4-hydroxyphenyl)propyl]amino]ethyl]pyrocatechol Hydrochloride; (RS)-Dobutamine Hydrochloride; DL-Dobutamine Hydrochloride; Dobutrex; Inotrex; 52663-81-7; 1,2-Benzenediol, 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-, hydrochloride (1:1), (±)-
EINECS	Contact for details

Quality Control

Our Dobutamine Hydrochloride is manufactured under strict quality management systems. It undergoes comprehensive analytical testing to meet stringent pharmacopeial standards, including identification, purity, assay, and impurity profile assessments. A Certificate of Analysis (COA) is provided with each batch, detailing compliance with relevant specifications. We support requirements for cGMP and ICH Q7 guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Optical Rotation	-0.10° to +0.10° (c = 5 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.