Description

L-Aspartic Acid-Ul-14C is a uniformly carbon-14 labeled isotopologue of the essential amino acid L-aspartic acid, identified by CAS NO 52526-39-3. This radiolabeled compound is a critical tool for tracing metabolic pathways, enabling precise quantification and visualization in biochemical and pharmacokinetic studies. It is primarily utilized by researchers and scientists in the pharmaceutical, biotechnology, and agrochemical industries for advanced research in drug development, metabolic engineering, and nutritional studies.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a tracer to study the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities and biologics.
• Biochemical Pathway Analysis: Essential for elucidating the Krebs cycle (TCA cycle), urea cycle, and amino acid biosynthesis and degradation pathways in cellular metabolism.
• Protein and Peptide Labeling Research: Incorporated into peptides and proteins to study their synthesis, turnover, localization, and interaction dynamics.
• Nutritional and Metabolic Research: Investigates the role of aspartic acid in neurotransmission, hormone regulation, and cellular energy production.
• Agrochemical Research: Employed in studies to understand the uptake, translocation, and metabolic fate of herbicides, pesticides, or plant growth regulators.
• In Vitro Diagnostic Assay Development: Serves as a key component in developing sensitive radioimmunoassays (RIA) and other clinical diagnostic tests.

Basic Information

Product Name	L-Aspartic Acid-Ul-14C
CAS No.	52526-39-3
Molecular Formula	C4H7NO4 (uniformly labeled with 14C)
Molecular Weight	~135.11 g/mol (exact mass depends on 14C enrichment)
Synonyms	(2S)-2-Aminobutanedioic acid-Ul-14C; Aspartic Acid-U-14C; L-Aspartic-14C(U) Acid; (S)-Aminobutanedioic Acid-14C(U); H-Asp-OH-U-14C; Aspartic Acid (Uniformly Labeled with Carbon-14); 14C-L-Aspartic Acid
EINECS	Contact for details

Quality Control

Every batch of our L-Aspartic Acid-Ul-14C is manufactured and analyzed under strict quality systems. We guarantee high radiochemical purity and chemical purity, with comprehensive testing including HPLC, NMR, and mass spectrometry to confirm identity, potency, and specific activity. Certificates of Analysis (COA) detailing radiochemical purity, chemical purity, specific activity, and solvent content are provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the container in a dry, inert atmosphere. Follow all applicable laboratory safety and radiation safety guidelines for handling and disposal.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customizable (mCi/mmol range)
Solvent (Residual)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.