Description

(R)-Thioridazine is a high-purity enantiomer of the phenothiazine derivative thioridazine, specifically the (R)-enantiomer. This compound is of significant interest in pharmaceutical research and development, particularly for studying stereospecific biological activity and pharmacokinetics. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in chiral drug discovery, neuroscience research, and analytical method development.

Application

• Chiral Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Neuroscience Research: Used as a reference standard or experimental compound in studies investigating neurological pathways and receptor interactions.
• Analytical Standard: Employed for method development, validation, and quality control in chromatographic assays (e.g., HPLC, Chiral HPLC) to separate and quantify enantiomers.
• Metabolite Studies: Utilized in pharmacokinetic and metabolic research to understand the disposition of the (R)-enantiomer.
• Pharmacology Reference: Acts as a controlled substance for comparative studies on the efficacy and side-effect profiles of different stereoisomers.

Basic Information

Item	Detail
Product Name	(R)-Thioridazine
CAS No.	52496-67-0
Molecular Formula	C21H26N2S2
Molecular Weight	370.57 g/mol
Synonyms	(R)-(-)-Thioridazine; (R)-Thioridazine Hydrochloride (salt form); Levothioridazine; (-)-Thioridazine; (R)-10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)-10H-phenothiazine; Mellaril (R-enantiomer); Novoridazine (R-enantiomer); Ridazine (R-enantiomer)
EINECS	Contact for details

Quality Control

Our (R)-Thioridazine is manufactured under strict quality management systems to ensure high enantiomeric purity and chemical integrity. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, identity confirmation by IR and NMR, and purity assessment. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.