Description

2-Chloro-4-Hydrazinopyrimidine is a versatile pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and hydrazino substituents, makes it a valuable precursor for constructing complex heterocyclic systems, particularly in the development of active pharmaceutical ingredients. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require reliable, high-quality raw materials for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of various drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Research: Used as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Employed in the construction of complex heterocyclic compounds for material science and specialty chemistry applications.
• Bioconjugation Chemistry: The reactive hydrazino group can be utilized for labeling and modifying biomolecules.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts.
• Academic & Industrial R&D: A fundamental reagent for exploring new chemical reactions and methodologies in organic chemistry.

Basic Information

Product Name	2-Chloro-4-Hydrazinopyrimidine
CAS No.	52476-87-6
Molecular Formula	C4H5ClN4
Molecular Weight	144.56 g/mol
Synonyms	4-Hydrazino-2-chloropyrimidine; 2-Chloro-4-hydrazinylpyrimidine; 2-Chloropyrimidin-4-ylhydrazine; 2-Chloro-4-pyrimidinylhydrazine; 4-Hydrazinyl-2-chloropyrimidine; 2-Chloro-4-hydrazino-pyrimidine; 2-Chloro-4-hydrazinopyrimidine; 2-Chloro-4-hydrazino-1,3-diazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Hydrazinopyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.